Main Missions

Here is the entire list of all the main missions in the game of Fallout 4.

1. War Never Changes (given by: Player Character) (starting point: Sanctuary Hills (pre-war))
2. Out Of Time (given by: Player Character) (starting point: Vault 111, Sanctuary Hills)
3. Jewel Of The Commonwealth (given by: Mama Murphy) (starting point: Sanctuary Hills)
4. Unlikely Valentine (given by: Ellie Perkins) (starting point: Valentine Detective Agency, 3rd St, Diamond City)
5. Getting A Clue (given by: Det. Nick Valentine) (starting point: Valentine Detective Agency, 3rd St, Diamond City)
6. Reunions (given by: Det. Nick Valentine) (starting point: Valentine Detective Agency, 3rd St, Diamond City)
7. Dangerous Minds (given by: Det. Nick Valentine) (starting point: Valentine Detective Agency, 3rd St, Diamond City)
8. The Glowing Sea (given by: Dr. Amari) (starting point: Dr. Amari's Lab at The Memory Den, State St, Goodneighbor)
9. Hunter/Hunted (given by: Dr. Brian Virgil) (starting point: Virgil's Secret Lab at Rocky Cave near Crater Of Atom at The Glowing Sea)
10. The Molecular Level (given by: Dr. Brian Virgil) (starting point: Virgil's Secret Lab at Rocky Cave near Crater Of Atom at The Glowing Sea)
11. Institutionalized (given by: Father) (starting point: The Institute, Cambridge Ave, Cambridge)
12. Mass Fusion (given by: main factions only) (starting point: anywhere)
13. The Nuclear Option (given by: main factions only) (starting point: anywhere)